Welcome to CD Bioarticles, your primary partner in the forefront of biobased nanoparticle design. As the global demand for sustainable and biocompatible materials continues to grow, we are at the forefront of providing comprehensive services dedicated to creating and optimizing nanoparticles from renewable biological sources. Our mission is to harness the power of nature to provide innovative solutions for a wide range of applications, including drug delivery, diagnostics, environmental remediation, and advanced materials. At CD Bioarticles, we combine our profound scientific expertise with state-of-the-art technology to transform your ideas into tangible, high-performance bio-based nanoparticles.
Figure 1. Biobased Nanoparticles Design Service.
Why Choose Biobased Nanoparticles?
Biobased nanoparticles represent a paradigm shift in traditional synthetic materials. Unlike their peers, they have several distinct advantages:
- Sustainability: They come from renewable raw materials such as cellulose, lignin, chitin, and protein, reducing our dependence on fossil fuels and minimizing our impact on the environment.
- Biocompatibility: Many biobased materials can be naturally recognized by biological systems, making them ideal choices for biomedical applications where minimizing toxicity and immune reactions is crucial.
- Biodegradability: These nanoparticles can be designed to degrade harmlessly in the environment, addressing growing concerns about nanoparticle accumulation and long-term ecological impacts.
- Adjustable features: The rich chemical diversity of biopolymers allows for precise control of physical and chemical properties, enabling the creation of nanoparticles with customized sizes, shapes, and surface functionalities.
Our services leverage these inherent advantages to provide you with products that are not only effective, but also comply with the principles of green chemistry and sustainable innovation.
Our Services
At CD Bioarticles, we offer a flexible and collaborative design process that allows you to choose the level of involvement that suits your project. Our services are classified to meet various needs from initial concept validation to large-scale production.
- Consultation and feasibility study
Every great project begins with a solid foundation. Our expert team will work closely with you to understand your specific application, performance requirements, and expected results. Then, we will conduct a thorough feasibility study to evaluate potential biobased materials, synthetic routes, and characterization methods. This stage ensures that your project is technically sound and prepared for success, saving you valuable time and resources.
- Material selection and procurement
The performance of bio based nanoparticles is fundamentally related to their source materials. We have extensive experience in various biobased polymers, including:
Cellulose: From microcrystalline cellulose to nanocellulose fibers, it is a multifunctional platform for structural and drug delivery applications.
Lignin: an aromatic polymer rich in antioxidants, ideal for UV protection and controlled release.
Chitin/Chitosan: Derived from the shell of crustaceans, it has excellent biocompatibility and antibacterial properties.
Proteins and peptides: including silk fibroin, collagen, and plant proteins, have excellent biodegradability and biological activity.
Polysaccharides: such as starch, alginate and glucan, are widely used in hydrogels and controlled release systems.
We assist in selecting the most suitable materials and provide high-quality procurement to ensure consistency and reliability.
- Synthesis and Manufacturing
Our state-of-the-art laboratory is equipped with a complete set of synthesis and manufacturing technologies. We use various top-down and bottom-up methods to create biobased nanoparticles, precisely controlling their morphology and size.
Top down approach: mechanical and chemical processing to decompose block like biobased materials into nanoscale particles. Examples include high-pressure homogenization and ball milling.
Bottom up approach: self-assembly and controlled precipitation techniques to construct nanoparticles from molecular precursors. This includes ion gel and solvent replacement methods.
We can produce a range of nanoparticle types, including spherical nanoparticles, nanorods, nanosheets, and core-shell structures, all of which can be customized according to your specifications.
- Surface functionalization and modification
In order to unleash the full potential of biobased nanoparticles, surface chemistry is crucial. Our functional services can connect targeted ligands, therapeutic agents, and reporter molecules. We can modify the surface of nanoparticles to:
Improve stability: prevent aggregation and increase cycle time by grafting polymers such as PEG.
Enhanced targeting: Delivery to specific cells or tissues through coupling antibodies, peptides, or aptamers.
Increasing drug loading: By modifying the surface to enhance the affinity for specific therapeutic payloads.
Control release kinetics: by adding smart polymers that are responsive to pH, temperature, or light.
Quality control is crucial. We provide a comprehensive characterization service to ensure that your nanoparticles meet the highest standards. Our analytical skills include:
Particle size and morphology: dynamic light scattering (DLS), transmission electron microscopy (TEM), and scanning electron microscopy (SEM).
Surface charge: Zeta potential measurement, used to evaluate stability and interactions with biological systems.
Chemical composition: Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR) spectroscopy.
Drug loading and encapsulation efficiency: High performance liquid chromatography (HPLC) and UV visible spectroscopy.
Biocompatibility and Cytotoxicity: In vitro Cell Detection for Evaluating Cell Uptake and Toxicity.
Our Advantages
Sustainable development
Our commitment to green synthesis reduces the impact on the environment and aligns with our customers' goals for environmentally friendly products.
Biocompatibility expertise
Professional knowledge in designing safe interactions between nanoparticles and biological systems is crucial for biomedical and cosmetic applications.
Scalability
From laboratory scale prototypes to a solid track record in industrial production, ensuring a seamless transition from development to commercialization.
Workflow
Summary
Biobased nanoparticles represent a paradigm shift in traditional synthetic materials. Unlike peers, many biobased materials can be naturally recognized by biological systems, making them ideal choices for biomedical applications where minimizing toxicity and immune reactions is crucial. The rich chemical diversity of biopolymers allows for precise control of their physical and chemical properties, enabling the creation of nanoparticles with customized sizes, shapes, and surface functionalities. At CD Bioparticles, we combine deep scientific expertise with state-of-the-art technology to transform your ideas into tangible, high-performance biobased nanoparticles.
