CD Bioparticles

Silica Nanomaterials Design Service

At CD Bioparticles, we recognize the unparalleled versatility and wide applicability of silica nanomaterials. Silicon dioxide nanomaterials have adjustable porosity, high surface area, excellent biocompatibility, chemical inertness, and easy surface functionalization, and are at the forefront of innovation in countless fields, from drug delivery and diagnosis to catalysis, separation, and advanced electronic technology. However, designing and synthesizing ideal silica nanomaterials requires specialized knowledge and precise control over their complex structure, morphology, and surface chemistry. CD Bioparticles provides comprehensive design services for silica nanomaterials, offering customized solutions that meet your specific research and industrial needs. Our end-to-end service covers everything from initial conceptualization and custom synthesis to rigorous characterization and optimization, ensuring that your silica nanomaterials are perfectly designed to achieve optimal performance.

Polymer Nanoparticle Design ServicesFigure 1. Silica Nanomaterials Design Service.

Why Choose Silica Nanomaterials?

Silicon dioxide nanomaterials include various structures such as solid silicon dioxide nanoparticles, mesoporous silicon dioxide nanoparticles (MSN), and hollow silicon dioxide spheres, which have a series of remarkable advantages:

  • Excellent versatility: Silicon dioxide can be designed in various forms (spheres, rods, tubes, films) with precise control over size, porosity, and surface chemistry.
  • High specific surface area and adjustable pores: Especially mesoporous silica, with incredible high surface area and pore volume, makes it an ideal choice for adsorption, catalysis, and high-capacity loading of various active agents. The aperture can be precisely adjusted from 2nm to 50nm.
  • Biocompatibility and low toxicity: Amorphous silica is generally considered biocompatible and non-toxic, making it suitable for biomedical applications such as drug delivery and imaging.
  • Chemical and thermal stability: Silicon dioxide nanomaterials have excellent chemical inertness and thermal stability, enabling them to withstand harsh environments and various processing conditions.

Our Services

At CD Bioparticles, we offer a comprehensive suite of services to address the unique requirements of silica nanomaterial development. Each service is customizable, ensuring alignment with your application's performance criteria.

Custom Silica Nanoparticle Synthesis

Our core service focuses on the precision synthesis of silica nanoparticles with controlled properties. We specialize in tuning:

  • Size: From 5 nm to 500 nm, with narrow size distribution (polydispersity index < 0.1) for consistent performance.
  • Morphology: Spherical, rod-shaped, cubic, or mesoporous structures, tailored to enhance surface area or functional capacity.
  • Porosity: Controlled pore sizes (2–50 nm) for applications requiring high loading capacity, such as drug delivery or catalysis.

Our synthesis protocols, including modified Stöber methods and reverse microemulsion techniques, ensure reproducibility across batches, critical for long-term research or scaling to production.

Surface Functionalization

To enhance compatibility and functionality, we offer advanced surface modification services. These include:

  • Chemical functionalization (amination, carboxylation, or thiolation) for improved reactivity.
  • Bioconjugation with proteins, peptides, or antibodies for targeted applications in biomedicine.
  • PEGylation and stealth coatings to reduce immunogenicity and extend circulation time in biological systems.

Each functionalization step is validated through rigorous testing to ensure stability and activity.

Silica Composite Nanomaterials

We design hybrid nanomaterials by integrating silica with other functional components, expanding application potential:

  • Silica-coated magnetic nanoparticles for imaging and separation technologies.
  • Metal-doped silica (e.g., gold, silver) for enhanced catalytic activity or plasmonic properties.
  • Quantum dot-silica composites for multimodal imaging and sensing.

Characterization & Quality Control

Every batch undergoes comprehensive analysis using state-of-the-art techniques:

  • Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM) for size and morphology verification.
  • Brunauer-Emmett-Teller (BET) analysis to measure surface area and porosity.
  • Zeta potential measurement to assess colloidal stability.
  • Fourier-Transform Infrared Spectroscopy (FTIR) to confirm surface functionalization.

We provide detailed characterization reports to ensure transparency and confidence in material performance.

Aapplication

The silica nanomaterials designed by CD Bioparticles have achieved breakthroughs in multiple fields:

  • Drug Delivery: Encapsulation and targeted delivery of small molecules, biologics, genes, and vaccines for various therapeutic areas, including cancer, infectious diseases, and regenerative medicine.
  • Diagnostics & Bioimaging: Development of contrast agents for MRI, CT, and ultrasound, as well as fluorescent probes for optical imaging and in vitro diagnostics.
  • Biosensing: Surface engineered silica for sensitive detection of biomarkers, pathogens, and environmental pollutants.
  • Catalysis: High surface area silica support, used for industrial catalytic reactions to improve efficiency and selectivity.
  • Energy storage: A silicon-based material used for battery electrodes and separators, which can improve energy density and cycle life.

Our Advantages

Chemical and Thermal Stability

Silica nanomaterials exhibit excellent chemical inertness and thermal stability, allowing them to withstand harsh environments and diverse processing conditions.

Biocompatibility

Amorphous silica is generally considered biocompatible and non-toxic, making it suitable for biomedical applications such as drug delivery and imaging.

Optical Transparency

Silica is optically transparent across a wide range of wavelengths, which is advantageous for imaging and optical sensing applications.

Workflow

Requirements Gathering

Design and Proposal

Synthesis and Optimization

Quality Control

Delivery

We streamline collaboration to deliver tailored solutions efficiently:

  • Consultation: Our team works with you to define requirements, including material properties, application goals, and scale. We provide expert recommendations to optimize design.
  • Proposal & Design: Based on your needs, we develop a detailed plan with timelines, costs, and technical specifications for approval.
  • Synthesis & Optimization: We execute synthesis using validated protocols, with iterative testing to refine properties as needed.
  • Characterization: Comprehensive testing ensures materials meet specifications, with a detailed report provided for review.
  • Delivery & Support: Prompt delivery with technical support post-delivery, including assistance with integration into your workflow.

Our professional knowledge and state-of-the-art facilities

CD Bioparticles is supported by an experienced team of scientists and engineers specializing in materials science, chemistry, and nanotechnology. Our cutting-edge laboratory is equipped with advanced synthesis equipment and comprehensive analytical instruments, enabling us to precisely control various aspects of the design and characterization of silica nanomaterials. We are committed to providing high-quality, reproducible, and reliable results, adhering to strict quality control protocols throughout the entire development process. We are committed to innovation and customer success, which makes us an ideal partner for challenging silica nanomaterials projects.

Summary

With over 15 years of expertise in the field of nanomaterials science, CD Bioparticles is a global leader in providing tailored silica nanomaterials solutions for research, pharmaceutical, and industrial applications. Our team of materials scientists, chemists, and nanotechnology experts combines cutting-edge synthesis techniques with strict quality control to provide silica nanoparticles optimized for specific customer needs. We are proud to bridge the gap between scientific innovation and practical applications, enabling researchers and industries to advance their work in precision engineering nanomaterials.