CD Bioparticles is a global leading provider of nanoparticles and microparticles, and their surface coatings for research and commercial purposes. CD Bioparticles has been operating for many years, focusing on the pharmaceutical and life science industries. We offer magnetic bead conjugation services to help researchers customize nanoparticles and magnetic beads with improved performance and unique biological functionality for specific applications, including immunoassays, drug discovery, therapeutics and drug delivery, diagnostics, bioimaging, gene editing, and various research and development projects.
Overview
Our custom magnetic bead conjugation services are tailored for the requirements of academic and research laboratories, research institutes, and pharmaceutical and biotechnology companies around the world. At CD Bioparticles, we provide surface functionalization, antibody immobilization, biomolecule conjugation, and other magnetic bead modification and conjugation services to meet your exact research needs, in small- and large-scale quantities, with the highest level of quality, reproducibility, and scalability.
Applications
- Multiplexed Diagnostics: Designing assays that can detect or capture multiple analytes simultaneously for increased throughput and efficiency.
- Targeted drug delivery: Engineering magnetic beads can deliver therapeutic agents to specific cell types or tissues under the influence of an external magnetic field.
- Cell isolation and separation: Create highly specific and efficient systems for isolating rare cell populations from complex biological samples.
Our Services
CD Bioparticles provides a fully customizable service, from initial concept to final product delivery. Our process begins with a detailed discussion of your project requirements, including the target molecule(s) to be conjugated, the desired functionality of the final product, and the specific application(s) the conjugated beads will be used for. Based on this, we propose a tailor-made strategy that may involve:
Customized composite material design
We work closely with clients to tailor composite materials for their specific applications. This includes selecting appropriate magnetic beads (such as iron oxide, polymer coatings) and functional components (such as proteins, peptides, nanoparticles, polymers, fluorescent probes). We optimized parameters such as component ratio, conjugate density, and surface modification to achieve the desired functionality.
Multi component conjugation
Our expertise enables us to conjugate multiple functional components onto a single magnetic bead. We can ensure stable and functional binding, whether by combining targeted ligands with therapeutic agents or fluorescent labeling with adsorbent materials.
Surface modification and functionalization
We provide surface modification services to improve the compatibility and functionality of magnetic beads. This includes using polymer coatings to improve stability, introducing reactive groups for subsequent conjugation, and modifying surface charges to control interactions with other molecules.
Workflow
Synthesis and Optimization
| Process | Descriptions |
|---|
| Consultation and project definition | We discuss your project details and requirements with our technical team.
We define the target biomolecule, functionality, and application |
| Material preparation and optimization | We prepare the magnetic beads or nanoparticles for the conjugation process.
We optimize the conjugation chemistry and reaction conditions |
| Conjugation and purification | We perform the conjugation reaction using our optimized protocols.
We purify the conjugated product to remove unbound biomolecules and impurities |
| Quality control and characterization | We conduct QC testing using fluorescence, UV-Vis, and LC-MS methods.
We provide COA (Certificate of Analysis) with detailed specifications |
| Scale-up and delivery | We scale up the production for research or commercial use.
We deliver the final product in GMP or non-GMP grade as required. |
Our Advantages
Expertise and Experience
Our team comprises highly skilled scientists with extensive experience in magnetic materials, surface chemistry, and biomolecule conjugation. Our team of scientists and technicians has a wealth of experience in magnetic bead antibody conjugation.
Customization and flexibility
We understand that every customer has different needs, so we provide highly customizable services. We can adjust the process to meet your specific requirements, whether it's customized conjugation schemes, unique magnetic bead selection, or specialized packaging.
Advanced Technology
We use the latest technology and state-of-the-art facilities to ensure that you receive the highest quality conjugates. Our laboratory is equipped with advanced conjugation, purification, and quality testing instruments to precisely control the conjugation process.
Summary
The magnetic bead multifunctional composite material bonding service of CD Bioparticles provides a gateway for innovative material solutions, combining the multifunctionality of magnetic beads with multifunctional components to address complex challenges. Our customized methods, advanced conjugation technology, and commitment to quality ensure that customers receive composite materials tailored to their specific needs. Our services cover fields such as biomedical research, environmental science, and advanced materials, supporting innovation and driving progress.
1. What is the minimum order quantity for custom conjugation services?
We offer both laboratory-grade and commercial-grade services in small scale, with the minimum order quantity depending on the specific project and conjugation method.
2. What types of biomolecules can bind to magnetic beads?
We can couple various biomolecules, including antibodies, proteins, peptides, enzymes, nucleic acids (DNA/RNA), aptamers, small molecules, and carbohydrates. We also provide coupling of non biological molecules, such as fluorescent groups, nanoparticles, and various chemical groups.
3. What is the typical turnaround time for custom conjugate projects?
The turnaround time varies depending on the complexity of the project, the specific materials required, and the level of functionality required. Once we understand your specific requirements, we will provide a detailed schedule during the initial consultation phase.
