CD Bioparticles

TEM Nanoparticle Analysis

Transmission Electron Microscopy (TEM) has become an indispensable tool in the field of nanoparticle research and application. It enables direct observation of nanoparticles at the atomic and molecular levels, providing crucial information for understanding their properties and functions. At CD Bioparticles, we offer professional TEM nanoparticle analysis services, covering all aspects from sample preparation to data interpretation. Our services are widely used in materials science, biomedicine, environmental science, and other fields, helping clients accurately grasp the characteristics of nanoparticles and promoting the development and application of related products and technologies. With advanced TEM equipment and a team of experienced professionals, we are committed to providing high-quality, reliable, and efficient analysis services to meet the diverse needs of our clients.

TEM Nanoparticle Analysis.Figure 1. TEM Nanoparticle Analysis.

Unrivaled Technical Expertise

Nanoparticles have unique physical, chemical, and biological properties due to their small size and large specific surface area, which make them have broad application prospects in many fields. However, these properties are closely related to their morphology, size, structure, and composition. Therefore, accurate characterization of nanoparticles is the key to studying their properties and applications.Transmission Electron Microscopy (TEM) is a powerful analytical technique that uses a high-energy electron beam to pass through a thin sample, and the electrons interact with the sample to form an image. Compared with other microscopy techniques, TEM has extremely high spatial resolution, which can reach the atomic level, allowing us to observe the internal structure and morphology of nanoparticles in detail. It can not only determine the size, shape, and distribution of nanoparticles but also analyze their crystal structure, elemental composition, and interface characteristics.

Our Services

1. High-Resolution TEM (HRTEM) Imaging

We provide ultra-high-resolution imaging to observe nanoparticle morphology, lattice fringes, and defects at the atomic scale. This is essential for understanding growth mechanisms, structural integrity, and surface modifications.

2. Particle Size and Shape Distribution Analysis

Using advanced image processing software, we measure and statistically analyze nanoparticle size distributions, aspect ratios, and aggregation states. This data is critical for reproducibility and performance evaluation.

3. Crystallographic Analysis (SAED & HRTEM)

  • Selected Area Electron Diffraction (SAED): Identifies crystal phases, lattice parameters, and preferred orientations.
  • High-Resolution TEM (HRTEM): Directly visualizes atomic arrangements and defects (dislocations, stacking faults).

4. Elemental Composition Mapping (EDS & EELS)

  • Energy-Dispersive X-ray Spectroscopy (EDS): Provides elemental identification and distribution within nanoparticles.
  • Electron Energy Loss Spectroscopy (EELS): Offers high sensitivity for light elements (e.g., C, N, O) and oxidation state analysis.

5. In-Situ TEM Analysis

We offer dynamic observations of nanoparticles under different conditions (heating, cooling, gas exposure, or mechanical stress) to study real-time transformations and reactions.

6. STEM Imaging (HAADF & BF-STEM)

  • High-Angle Annular Dark-Field (HAADF) STEM: Enhances Z-contrast imaging for heavy elements.
  • Bright-Field STEM (BF-STEM): Provides complementary contrast for light elements.

7. 3D Tomography Reconstruction

By tilting the sample and acquiring multiple images, we reconstruct 3D nanoparticle structures, offering insights into porosity, agglomeration, and internal architectures.

Our Advantages

Professional Technical Team

Our technical team is composed of experienced TEM analysts and material scientists who have rich experience in nanoparticle analysis. They are proficient in the operation of TEM equipment and data analysis, and can solve various complex problems in the analysis process. They can also provide professional technical guidance and suggestions.

Advanced Equipment and Technology

We are equipped with the latest generation of TEM equipment, which has high spatial resolution (up to 0.1 nm) and high signal-to-noise ratio, ensuring that we can observe the fine structure of nanoparticles. At the same time, we continue to introduce new technologies and methods to improve the level of analysis and meet the increasing needs of clients.

Customized Services

We understand that different clients have different needs for nanoparticle analysis. Therefore, we provide customized analysis services according to the client's specific requirements. Whether it is a routine analysis project or a complex research project, we can formulate a suitable analysis plan to meet the client's needs.

Service Time and Process

  • Standard service: 5-10 working days, suitable for routine analysis needs.
  • Urgent service: 2-5 working days, applicable to urgent projects.
  • Service process: After the customer submits the sample, we will proceed with sample preparation, microscopy imaging, and data analysis, and provide the final report within the specified time.

Workflow

Requirements Gathering

Design and Proposal

Synthesis and Optimization

Quality Control

Delivery

Summary

TEM nanoparticle analysis is an important means to understand the properties and functions of nanoparticles, and plays a crucial role in the research and application of nanotechnology. At CD Bioparticles, we are committed to providing high-quality, professional TEM nanoparticle analysis services to help clients overcome technical challenges in nanoparticle research and production. With advanced equipment, professional technical team, strict quality control, and customized services, we can provide comprehensive and in-depth analysis results for clients, providing strong support for the development of new materials, the research of biomedical products, and the solution of environmental problems.